Chiral metallic anticancer drugs: A brief-review
نویسندگان
چکیده
Chiral metallic drugs are becoming the hottest point of discussion in field medicinal chemistry. As we know that more than 80% chiral nature, and prescribed racemic form. The main problem with is different biological activities enantiomers. This because human body has a environment, as there presence protein, carbohydrates, enzymes, other macromolecules. Hence, if anticancer drug being to patient form, it means two or prescribed. Therefore, separation analysis important for improving quality medication. Many metal complexes used drugs, but conditions become critical they have chirality moiety, which exist forms. Because complex metals termed complex. Of course, enantioseparation must be done before their prescription. Enantioseparation will not only provide pharmaceutically active form also reduce side effects caused by mixture. accessible article reviews having ruthenium, osmium, palladium, gold, silver, platinum, etc. central atoms. Besides, future perspectives regarding role discussed.
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ژورنال
عنوان ژورنال: European Journal of Chemistry
سال: 2022
ISSN: ['2153-2249', '2153-2257']
DOI: https://doi.org/10.5155/eurjchem.13.4.483-490.2312